diff --git a/runtimes/cmake/Modules/HandleLibC.cmake b/runtimes/cmake/Modules/HandleLibC.cmake
index aa076441345d..9b6749dd2615 100644
--- a/runtimes/cmake/Modules/HandleLibC.cmake
+++ b/runtimes/cmake/Modules/HandleLibC.cmake
@@ -10,6 +10,10 @@
 
 include_guard(GLOBAL)
 
+if(TARGET runtimes-libc-headers)
+  return()
+endif()
+
 set(RUNTIMES_SUPPORTED_C_LIBRARIES system llvm-libc picolibc newlib)
 set(RUNTIMES_USE_LIBC "system" CACHE STRING "Specify C library to use. Supported values are ${RUNTIMES_SUPPORTED_C_LIBRARIES}.")
 if (NOT "${RUNTIMES_USE_LIBC}" IN_LIST RUNTIMES_SUPPORTED_C_LIBRARIES)